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Sex-differential mortality after routine vaccinations in urban Guinea-Bissau

26 July 2016

In addition to the targeted effects, vaccines may also have non-specific effects (NSEs) on child mortality. The NSEs are often sex-differential. Hence, changes in sex-differences in child mortality by vaccination status is important in assessing the effects of new vaccines.

Different Bacillus Calmette-Guerin (BCG) vaccine strains may have different non-specific effects

26 July 2016

We assessed the effect of two BCG strains (Danish and Russian) on childhood morbidity and BCG scarification in Guinea-Bissau.

Vaccines against tuberculosis and smallpox may reduce overall mortality

6 July 2016

What if we affected health negatively when we phased out the two vaccines against smallpox and tuberculosis in the 1970s and 1980s in Denmark? Studies on non-specific effects of vaccines indicate that such live attenuated vaccines may reduce morbidity and mortality – not related to the vaccine-targeted diseases - through epigenetic changes of the innate immune system.

Evaluation of the effect of vaccines on overall health in Danish children

19 May 2016

The first results from Signe Sørups Postdoc studies on Danish children show that oral polio vaccine is associated with lower rate of admissions with infections.

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